Monoclonal gammopathy of undetermined significance, a common precursor to multiple myeloma, developed significantly more in individuals with obesity, according to a study published in Blood Advances.
Those who smoked heavily and those who slept less than 6 hours per day had a higher occurrence of monoclonal gammopathy of undetermined significance (MGUS) as well, while physically active individuals had lower rates.
“While obesity is an established modifiable risk factor for multiple myeloma, the data have not yet been clear regarding its association with myeloma precursor conditions,”