Clin Nucl Med. 2024 Jun 3. doi: 10.1097/RLU.0000000000005296. Online ahead of print.
ABSTRACT
A 60-year-old woman underwent whole-body contrast-enhanced CT because multiple myeloma was suspected. The contrast-enhanced CT showed pancreatic enlargement without main pancreatic duct dilatation and increased peripancreatic fat tissue. 18F-FDG PET/CT demonstrated diffuse uptake in the enlargement of the pancreas, left and right ventricles, and vertebral column. Biopsy and bone marrow aspiration cytology revealed amyloid light-chain amyloidosis associated with multiple myeloma. Chemotherapy was performed; 18F-FDG uptake in the pancreas then disappeared, and the pancreatic enlargement decreased. When diffuse 18F-FDG uptake in pancreatic enlargement is observed in multiple myeloma patients, amyloid light-chain amyloidosis should be considered.
PMID:38861377 | DOI:10.1097/RLU.0000000000005296