Inherited variants in DNA repair genes such as BRCA1 and BRCA2 may increase risk for multiple myeloma, according to results of a retrospective study.
Patients with pathogenic germline variants exhibited increased likelihood of having a family or personal history of cancer, or of getting diagnosed at a younger age.
“Definitively, this changes care for patients with myeloma,” Kenan Onel, MD, PhD, chief of clinical genomics and director of the Center for Precision Oncology and Cancer Prevention at Roswell Park Comprehensive Cancer Center, told Healio.
Prior research showed individuals
