Clin Case Rep. 2024 Jul 3;12(7):e9154. doi: 10.1002/ccr3.9154. eCollection 2024 Jul.

ABSTRACT

Down syndrome (DS), characterized by trisomy 21, significantly increases susceptibility to leukemia, although the occurrence of multiple myeloma (MM) in DS is exceedingly rare. This report details the case of a 45-year-old female with DS who was diagnosed with MM, highlighting diagnostic and therapeutic complexities. It emphasizes the importance of tailored therapeutic strategies for treating MM in individuals with DS and the need for specialized approaches in these cases.

PMID:38962468 | PMC:PMC11220454 | DOI:10.1002/ccr3.9154