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Melflufen and Dexamethasone in Heavily Pretreated Relapsed and Refractory Multiple Myeloma.

by MM360 Staff | Jun 10, 2021 | Publications

Melphalan flufenamide (melflufen) is a first-in-class peptide-drug conjugate that targets aminopeptidases and rapidly and selectively releases alkylating agents into tumor cells. The phase II HORIZON trial evaluated the efficacy of […]

Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression.

by MM360 Staff | Jun 10, 2021 | Uncategorized

Smoldering multiple myeloma (SMM) is a precursor condition of multiple myeloma (MM) with a 10% annual risk of progression. Various prognostic models exist for risk stratification; however, those are based […]

Implementation of the International Myeloma Working Group reccomendations on renal impairment in multiple myeloma patients in routine clinical practice.

by MM360 Staff | Jun 10, 2021 | Uncategorized

Click here to read the full article @ Annals of oncology : official journal of the European Society for Medical Oncology

How We Approach Smoldering Multiple Myeloma.

by MM360 Staff | Jun 10, 2021 | Uncategorized

The Oncology Grand Rounds series is designed to place original reports published in the Journal into clinical context. A case presentation is followed by a description of diagnostic and management […]

Long-Term Follow-Up Results of Lenalidomide, Bortezomib, and Dexamethasone Induction Therapy and Risk-Adapted Maintenance Approach in Newly Diagnosed Multiple Myeloma.

by MM360 Staff | Jun 10, 2021 | Uncategorized

The combination of lenalidomide, bortezomib, and dexamethasone (RVD) is a highly effective and convenient induction regimen for both transplantation-eligible and -ineligible patients with myeloma. Here, we present the largest cohort […]
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