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Addition of daratumumab to standard triplet regimens achieved better survival in newly diagnosed multiple myeloma: a systematic review and meta-analysis of randomized controlled trials

by MM360 Staff | Nov 18, 2025 | Publications

Front Oncol. 2025 Oct 30;15:1619115. doi: 10.3389/fonc.2025.1619115. eCollection 2025. ABSTRACT BACKGROUND: Triplet regimens, such as bortezomib-lenalidomide-dexamethasone (VRd) and bortezomib-melphalan-prednisone (VMP), were standard treatments for newly diagnosed...

Inflammatory markers from routine blood tests predict survival in multiple myeloma: a Systematic Review and meta-analysis

by MM360 Staff | Nov 18, 2025 | Publications

Front Immunol. 2025 Oct 30;16:1669878. doi: 10.3389/fimmu.2025.1669878. eCollection 2025. ABSTRACT BACKGROUND: Multiple myeloma (MM) is an incurable hematologic malignancy marked by abnormal plasma cell proliferation. Inflammatory indices derived from routine blood...

The challenge of non-transplant eligible, newly diagnosed multiple myeloma

by MM360 Staff | Nov 15, 2025 | Publications

Leuk Lymphoma. 2025 Oct;66(10):1767-1777. doi: 10.1080/10428194.2025.2513676. Epub 2025 Jun 3. ABSTRACT Eligibility for autologous transplantation is a key factor for tailoring treatment decisions in patients with newly-diagnosed multiple myeloma. For non-eligible...

Optimizing oncology drug development: systematic review of 22 years of myeloma randomized controlled trials

by MM360 Staff | Nov 10, 2025 | Publications

J Natl Cancer Inst. 2025 Nov 9:djaf326. doi: 10.1093/jnci/djaf326. Online ahead of print. ABSTRACT INTRODUCTION: Although myeloma represents a key success story in oncology, some drugs have failed to meet primary endpoints in randomized controlled trials (RCTs),...

Efficacy of novel therapies for refractory and relapsed multiple myeloma in China: A scoping systematic review

by MM360 Staff | Nov 2, 2025 | Publications

Chin Med J (Engl). 2025 Oct 31. doi: 10.1097/CM9.0000000000003832. Online ahead of print. NO ABSTRACT PMID:41173804 | DOI:10.1097/CM9.0000000000003832

Comparative efficacy and safety of BCMA-targeted CAR T cells and BiTEs in relapsed/refractory multiple myeloma: a meta-analysis of interventional and real-world studies

by MM360 Staff | Oct 25, 2025 | Publications

Ann Hematol. 2025 Sep;104(9):4791-4809. doi: 10.1007/s00277-025-06524-6. Epub 2025 Sep 9. ABSTRACT Despite therapeutic advances, multiple myeloma (MM) remains incurable, especially in relapsed/refractory (R/R) cases. B-cell maturation antigen (BCMA) is a key target...
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