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Evaluation of anti-CD38 monoclonal antibody-based immunotherapy in multiple myeloma with renal insufficiency: a systematic review and meta-analysis

by | Feb 18, 2025 | Publications

Ther Adv Hematol. 2025 Feb 17;16:20406207251319593. doi: 10.1177/20406207251319593. eCollection 2025. ABSTRACT BACKGROUND: Renal impairment is one of the common characteristics of multiple myeloma (MM) and makes management of MM more complicated. Even though...

Bortezomib, thalidomide, and dexamethasone versus bortezomib, lenalidomide, and dexamethasone in transplant-eligible newly diagnosed multiple myeloma: a systemic review and meta-analysis

by | Feb 7, 2025 | Publications

Hematology. 2025 Dec;30(1):2462249. doi: 10.1080/16078454.2025.2462249. Epub 2025 Feb 6. ABSTRACT BACKGROUND: The current study aimed to compare treatment responses, the incidence of the need for auto-HSCT, and the occurrence of specific adverse events (AEs) between...

Management of CAR-T cell therapy in patients with multiple myeloma: a systematic review and expert consensus in Australia

by | Feb 5, 2025 | Publications

Front Oncol. 2025 Jan 21;14:1535869. doi: 10.3389/fonc.2024.1535869. eCollection 2024. ABSTRACT BACKGROUND: Regulatory bodies have recently approved chimeric antigen receptor (CAR)-T cell therapies for patients with multiple myeloma (MM), but the treatment process...

A Systematic Review and Meta-analysis on the Safety and Efficacy of CAR T Cell Therapy Targeting GPRC5D in Patients with Multiple Myeloma: A New Insight in Cancer Immunotherapy

by | Feb 4, 2025 | Publications

Anticancer Agents Med Chem. 2025 Jan 30. doi: 10.2174/0118715206350342241224073809. Online ahead of print. ABSTRACT BACKGROUND: Despite ongoing advances and introducing innovative therapeutic approaches for the treatment of multiple myeloma (MM), relapses are common,...

Efficacy and safety of anti-CD38 monoclonal antibodies-based therapy versus standard therapy in newly diagnosed multiple myeloma patients: a systematic review and meta-analysis

by | Jan 28, 2025 | Publications

Ther Adv Hematol. 2025 Jan 27;16:20406207251314289. doi: 10.1177/20406207251314289. eCollection 2025. ABSTRACT BACKGROUND: Anti-CD38 monoclonal antibodies (mAbs) have significantly changed the multiple myeloma treatment landscape. This meta-analysis compared the...

Patient-reported outcome domains in multiple myeloma randomized controlled trials and association with survival outcomes

by | Jan 8, 2025 | Publications

Ann Hematol. 2024 Dec;103(12):5849-5859. doi: 10.1007/s00277-024-06129-5. Epub 2024 Dec 7. ABSTRACT Patient-reported outcomes (PROs) are crucial endpoints in multiple myeloma (MM) randomized controlled trials (RCTs), yet there is significant variability in their...
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