Multiple myeloma: signaling pathways and targeted therapy

Mol Biomed. 2024 Jul 4;5(1):25. doi: 10.1186/s43556-024-00188-w. ABSTRACT Multiple myeloma (MM) is the second most common hematological malignancy of plasma cells, characterized by osteolytic bone lesions, anemia, hypercalcemia, renal failure, and the accumulation of...

Novel therapies for multiple myeloma

Rinsho Ketsueki. 2024;65(6):547-557. doi: 10.11406/rinketsu.65.547. ABSTRACT B-cell maturation antigen (BCMA)-targeting therapy is the most common approach to immunotherapy and cellular therapy for multiple myeloma (MM). Three major agents, CAR-T cells, bispecific...