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A Systematic Review of Modeling Approaches to Evaluate Treatments for Relapsed Refractory Multiple Myeloma: Critical Review and Considerations for Future Health Economic Models

by | Jun 26, 2024 | Publications

Pharmacoeconomics. 2024 Jun 25. doi: 10.1007/s40273-024-01399-3. Online ahead of print. ABSTRACT BACKGROUND AND OBJECTIVE: Multiple myeloma is a rare incurable hematological cancer in which most patients relapse or become refractory to treatment. This systematic...

Which factors are associated with adverse prognosis in multiple myeloma patients after surgery? – preliminary establishment and validation of the nomogram

by | Jun 26, 2024 | Publications

World J Surg Oncol. 2024 Jun 25;22(1):168. doi: 10.1186/s12957-024-03453-y. ABSTRACT BACKGROUND: To investigate the prognosis of patients with Multiple Myeloma (MM) after surgery, analyze the risk factors leading to adverse postoperative outcomes, and establish a...

Identification of lipid metabolism-related gene signature in the bone marrow microenvironment of multiple myelomas through deep analysis of transcriptomic data

by | Jun 25, 2024 | Publications

Clin Exp Med. 2024 Jun 25;24(1):136. doi: 10.1007/s10238-024-01398-w. ABSTRACT Dysregulated lipid metabolism in the bone marrow microenvironment (BMM) plays a vital role in multiple myeloma (MM) development, progression, and drug resistance. However, the exact...

18F-FDG PET/CT Unveils Coexistent Myelomatous Hepatosplenic and Thyroid Cartilage Involvement: A Rare Presentation in Multiple Myeloma

by | Jun 25, 2024 | Publications

Clin Nucl Med. 2024 Jun 25. doi: 10.1097/RLU.0000000000005326. Online ahead of print. ABSTRACT Extramedullary myelomatous disease is an aggressive condition where clonal plasma cells proliferate outside the bone marrow, allowing independent survival. This state is...

Clinician and administrator perspectives on outpatient administration of ciltacabtagene autoleucel in relapsed or refractory multiple myeloma

by | Jun 25, 2024 | Publications

Front Immunol. 2024 Jun 10;15:1405452. doi: 10.3389/fimmu.2024.1405452. eCollection 2024. ABSTRACT INTRODUCTION: Chimeric antigen receptor (CAR) T-cell therapy (CAR T therapy) is a treatment option for patients with relapsed or refractory multiple myeloma that has led...

Multiple myeloma incidence and mortality trends in the United States, 1999-2020

by | Jun 25, 2024 | Publications

Sci Rep. 2024 Jun 24;14(1):14564. doi: 10.1038/s41598-024-65590-4. ABSTRACT Multiple myeloma (MM) is a plasma cell disorder accounting for approximately 10% of hematologic malignancies. There is limited epidemiological evidence regarding the long-term trends and...
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