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Highlighting the role of long non-coding RNA (LncRNA) in multiple myeloma (MM) pathogenesis and response to therapy

by | Jun 8, 2024 | Publications

Med Oncol. 2024 Jun 7;41(7):171. doi: 10.1007/s12032-024-02392-8. ABSTRACT Transcripts longer than 200 nucleotides that are not translated into proteins are known as long non-coding RNAs, or lncRNAs. Now, they are becoming more significant as important regulators of...

Progression of monoclonal gammopathy of undetermined significance to multiple myeloma is associated with enhanced translational quality control and overall loss of surface antigens

by | Jun 8, 2024 | Publications

J Transl Med. 2024 Jun 7;22(1):548. doi: 10.1186/s12967-024-05345-x. ABSTRACT BACKGROUND: Despite significant advancements in treatment strategies, multiple myeloma remains incurable. Additionally, there is a distinct lack of reliable biomarkers that can guide initial...

Predictive factors for peripheral blood stem cell mobilization in multiple myeloma in the era of novel therapies: A single-center experience

by | Jun 8, 2024 | Publications

Cancer Med. 2024 Jun;13(11):e7356. doi: 10.1002/cam4.7356. ABSTRACT OBJECTIVE: Multiple myeloma (MM) is the leading indication of autologous hematopoietic stem cell transplantation. The aim of this study was to determine the incidence of mobilization failure and...

Proactive consultation of laboratory medicine increased diagnostic rate of multiple myeloma: One single center’s 12-year experience

by | Jun 7, 2024 | Publications

Medicine (Baltimore). 2024 Jun 7;103(23):e38523. doi: 10.1097/MD.0000000000038523. ABSTRACT Multiple myeloma (MM) was one of the hardest cancers to diagnose because of numerous nonspecific symptoms, leading to diagnostic delay. Proactive consultation of laboratory...

Assessing Outcomes in Patients With Multiple Myeloma Postautologous Stem Cell Transplantation: Contrasting the Effects of Melphalan Dosages at 200 mg/m(2) versus 140 mg/m(2)

by | Jun 7, 2024 | Publications

Clin Lymphoma Myeloma Leuk. 2024 May 7:S2152-2650(24)00177-0. doi: 10.1016/j.clml.2024.05.005. Online ahead of print. ABSTRACT BACKGROUND: No standard criteria for dose reduction exists for high-dose melphalan for autologous stem cell transplantation (ASCT) for...

Safety and feasibility analysis of rapid daratumumab infusion in Chinese patients with multiple myeloma

by | Jun 7, 2024 | Publications

Cancer Med. 2024 Jun;13(11):e7347. doi: 10.1002/cam4.7347. ABSTRACT BACKGROUND: With the increasing use of daratumumab (DARA)-containing regimens for multiple myeloma (MM) patients in China, the standard infusion time of DARA is long, with the potential for...
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