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Modest survival benefits of autologous stem cell transplantation in multiple myeloma with renal impairment: a critical appraisal of the pre-antibody era

by | Sep 18, 2024 | Publications

Clin Exp Med. 2024 Sep 9;24(1):215. doi: 10.1007/s10238-024-01481-2. ABSTRACT The benefit of high-dose melphalan followed by autologous hematopoietic stem cell transplantation (HDM-ASCT) for multiple myeloma (MM) patients with renal insufficiency (RI) is debated. A...

Meta-analysis of effectiveness and safety of proteasome inhibitor-dependent maintenance treatment for multiple myeloma a systematic review

by | Sep 18, 2024 | Publications

Heliyon. 2024 Aug 13;10(16):e36311. doi: 10.1016/j.heliyon.2024.e36311. eCollection 2024 Aug 30. ABSTRACT BACKGROUND: Even with significant advancements, treating multiple myeloma (MM) remains difficult. At present, the main treatment methods include combined...

Second primary malignancies after CAR T-cell therapy: A systematic review and meta-analysis of 5,517 lymphoma and myeloma patients

by | Sep 18, 2024 | Publications

Clin Cancer Res. 2024 Sep 11. doi: 10.1158/1078-0432.CCR-24-1798. Online ahead of print. ABSTRACT PURPOSE: CAR T-cell therapy is a potent immunotherapy for hematologic malignancies, but patients can develop long-term adverse events including second primary...

The acceptability of using wearable electronic devices to monitor physical activity of patients with Multiple Myeloma undergoing treatment: a systematic review

by | Sep 18, 2024 | Publications

Clin Hematol Int. 2024 Jul 29;6(3):38-53. doi: 10.46989/001c.121406. eCollection 2024. ABSTRACT INTRODUCTION: Multiple myeloma (MM) is diagnosed in 6,000 people in the UK yearly. A performance status measure, based on the patients’ reported level of physical...

Role of Autologous Transplant in Newly Diagnosed Multiple Myeloma Patients Treated with Novel Triplets: A Systematic Review and Meta-Analysis

by | Sep 18, 2024 | Publications

Acta Haematol. 2024 Sep 16:1-17. doi: 10.1159/000540232. Online ahead of print. ABSTRACT INTRODUCTION: High-dose therapy with melphalan followed by autologous stem cell transplant at the upfront setting (upfront ASCT) has significantly improved clinical outcomes of...

Evaluating early intervention in smoldering myeloma clinical trials: a systematic review

by | Sep 9, 2024 | Publications

Oncologist. 2024 Sep 5:oyae219. doi: 10.1093/oncolo/oyae219. Online ahead of print. ABSTRACT BACKGROUND: Smoldering multiple myeloma (SMM), an asymptomatic precursor of multiple myeloma (MM), carries a variable risk of progression to MM. There is little consensus on...
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