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Effect of Recombinant Human Thrombopoietin on Platelet Reconstitution after Autologous Peripheral Blood Stem Cell Transplantation in Patients with Multiple Myeloma

by | Apr 25, 2024 | Publications

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2024 Apr;32(2):505-511. doi: 10.19746/j.cnki.issn.1009-2137.2024.02.028. ABSTRACT OBJECTIVE: To analyze the effect of recombinant human thrombopoietin (rhTPO) on platelet (PLT) reconstitution after autologous peripheral blood stem...

Tandem autologous hematopoietic stem cell transplantation for patients with multiple myeloma: a systematic review and meta-analysis

by | Apr 24, 2024 | Publications

Hematology. 2024 Dec;29(1):2343164. doi: 10.1080/16078454.2024.2343164. Epub 2024 Apr 23. ABSTRACT To evaluate whether patients with multiple myeloma (MM) could benefit from tandem autologous hematopoietic stem cell transplantation (auto-HSCT), PubMed, Embase, Web of...

Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma

by | Apr 24, 2024 | Publications

Clin Cancer Res. 2024 Apr 23. doi: 10.1158/1078-0432.CCR-24-0210. Online ahead of print. ABSTRACT PURPOSE: Early intervention for High-Risk Smoldering Multiple Myeloma (HR-SMM) achieves deep and prolonged responses. It is unclear if beneficial outcomes are due to...

Plain Language Summary of the KarMMa-3 study of ide-cel or standard of care regimens in people with relapsed or refractory multiple myeloma

by | Apr 24, 2024 | Publications

Future Oncol. 2024 Apr 23. doi: 10.2217/fon-2023-0954. Online ahead of print. ABSTRACT WHAT IS THIS SUMMARY ABOUT?: This plain language summary describes the results of a Phase 3 study called KarMMa-3. In this ongoing study, researchers looked at a relatively new...

Exploring the role of histone deacetylase and histone deacetylase inhibitors in the context of multiple myeloma: mechanisms, therapeutic implications, and future perspectives

by | Apr 24, 2024 | Publications

Exp Hematol Oncol. 2024 Apr 23;13(1):45. doi: 10.1186/s40164-024-00507-5. ABSTRACT Histone deacetylase inhibitors (HDACis) are a significant category of pharmaceuticals that have developed in the past two decades to treat multiple myeloma. Four drugs in this category...

Immune escape of multiple myeloma cells results from low miR29b and the ensuing epigenetic silencing of proteasome genes

by | Apr 24, 2024 | Publications

Biomark Res. 2024 Apr 23;12(1):43. doi: 10.1186/s40364-024-00592-y. ABSTRACT BACKGROUND: Activation of CD28 on multiple myeloma (MM) plasma cells, by binding to CD80 and CD86 on dendritic cells, decreases proteasome subunit expression in the tumor cells and thereby...
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