Oncoimmunology. 2024 May 27;13(1):2360275. doi: 10.1080/2162402X.2024.2360275. eCollection 2024.
ABSTRACT
Recently, it was revealed that the high-risk, poor-prognosis downregulation of GABA type A receptor-associated protein (GABARAP) causes a defect in both autophagy and surface exposure of calreticulin (CALR) in multiple myeloma (MM) cells responding to bortezomib. Hence, GABARAP-defective MM cells fail to undergo immunogenic cell death.
PMID:38812570 | PMC:PMC11135808 | DOI:10.1080/2162402X.2024.2360275