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Comparison of trace elements in peripheral blood and bone marrow of newly diagnosed multiple myeloma patients

by | Apr 17, 2024 | Publications

Clin Exp Med. 2024 Apr 17;24(1):78. doi: 10.1007/s10238-024-01349-5. ABSTRACT Trace elements are essential micronutrients for the human body. Their roles are indispensable, as they are involved in a wide range of vital biological processes. In this study, we aimed to...

Comparative performance of scFv-based anti-BCMA CAR formats for improved T cell therapy in multiple myeloma

by | Apr 17, 2024 | Publications

Cancer Immunol Immunother. 2024 Apr 17;73(6):100. doi: 10.1007/s00262-024-03688-4. ABSTRACT In multiple myeloma (MM), B cell maturation antigen (BCMA)-directed CAR T cells have emerged as a novel therapy with potential for long-term disease control. Anti-BCMA CAR T...

Exploring the efficacy and safety of anti-BCMA chimeric antigen receptor T-cell therapy for multiple myeloma: Systematic review and meta-analysis

by | Apr 17, 2024 | Publications

Cytojournal. 2024 Mar 18;21:13. doi: 10.25259/Cytojournal_64_2023. eCollection 2024. ABSTRACT OBJECTIVE: Multiple myeloma (MM) is a bone marrow cancer that profoundly affects plasma cells involved in the immune response. Myeloma cells alter the average production of...

Practical Aspects of Immunotherapy: A Report from the 20th International Myeloma Society (IMS) Annual Meeting

by | Apr 17, 2024 | Publications

Clin Lymphoma Myeloma Leuk. 2024 Mar 22:S2152-2650(24)00112-5. doi: 10.1016/j.clml.2024.03.005. Online ahead of print. ABSTRACT Immunotherapeutic strategies, specifically T-cell-redirected therapies, have been transformative in the context of multiple myeloma (MM)....

Prognostic Implications of Circulating Plasma Cell Percentage in Multiple Myeloma and Primary Plasma Cell Leukemia Defined by New Criteria

by | Apr 17, 2024 | Publications

Acta Haematol. 2024 Apr 16. doi: 10.1159/000538658. Online ahead of print. ABSTRACT INTRODUCTION: The definition of primary plasma cell leukemia (pPCL) has been revised from ≥20% to ≥5% circulating plasma cells (CPC). However, the precise prognosis associated with CPC...

Current knowledge on therapeutic, diagnostic, and prognostics applications of exosomes in multiple myeloma: opportunities and challenges

by | Apr 17, 2024 | Publications

Arch Biochem Biophys. 2024 Apr 14:109994. doi: 10.1016/j.abb.2024.109994. Online ahead of print. ABSTRACT Interactions between the plasma cells and the BM microenvironment of Multiple myeloma (MM) take place through factors such as exosomes. Many studies have...
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